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Etoposide is a semisynthetic derivative of podophyllotoxin. The mechanism of action is associated with inhibition of topoisomerase II. Etoposide exerts a cytotoxic effect due to DNA damage. The drug blocks mitosis, causing cell death in the late G2 phase and S-phase mitoticheckogo cycle. High concentrations of the drug in causing cell lysis premitoticheckoy phase. Etoposide…

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It is effective against malaria pathogens resistant to other antimalarial drugs such as chloroquine, proguanil, pyrimethamine and the combination of pyrimethamine with sulfonamides.  Falciparum may develop resistance to mefloquine, mainly in Southeast Asia. In some regions, marked cross-resistance between mefloquine and halofantrine, mefloquine and quinine. The drug does not cause hemolysis associated primobolan depot with a…

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Antiulcer agent. A specific primobolan results  inhibitor of proton pump  metabolised in the gastric parietal cells to active sulfonamide derivatives that inactivate the sulfhydryl groups. Blocks the synthesis final stage of hydrochloric acid to decrease both basal and stimulated secretion regardless of the nature of the stimulus. Inhibition of production of hydrochloric acid at a…

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A specific inhibitor of proton pump  metabolised in the gastric parietal cells to active sulfonamide derivatives that inactivate the sulfhydryl groups. Blocks the final stage of hydrochloric acid secretion, lowering both basal and stimulated secretion, primobolan for sale irrespective of the nature of the stimulus. Inhibition of production of hydrochloric acid at a dose of 30…