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Ondansetron is a selective 5-HT receptor antagonist 3 (serotonin). Cytostatic drugs for chemotherapy and radiotherapy may cause an increase in the level of serotonin, which by activation of vagal afferent fibers containing receptors 5-HT 3 causes the gag reflex.Ondansetron inhibits occurrence gag reflex by blockade of 5-HT receptor 3 neuronal level both central and peripheral…